A review paper was published in the peer-reviewed journal Diagnostics, titled “Three-Dimensional Structure of Novel Liver Cancer Biomarker Liver Cancer-Specific Serine Protease Inhibitor Kazal (LC-SPIK) and Its Performance in Clinical Diagnosis of Hepatocellular Carcinoma (HCC)”. The paper analyzes the publicly available data on the LC-SPIK biomarker and its performance in detecting early stage liver cancer, which shows strong clinical performance in terms of specificity and sensitivity. New information in this paper also provides additional information for the three-dimensional structure of the LC-SPIK protein and how it differs from the normal, pancreatic form of the peptide.
Check out the open-access review paper in Diagnostics to learn more.